Somatic base editing to model oncogenic drivers in breast cancer
نویسندگان
چکیده
منابع مشابه
Targeting oncogenic drivers.
Cancer is a genetic disease caused by a series of somatic and/or germline mutations. The roles of oncogenes and tumor suppressors in cancer molecular origin have been well established. Targeting oncogene products has become an attractive therapeutic strategy with great clinical success, whereas tumor suppressors are considered 'undruggable' because current technology is not able to restore tumo...
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ژورنال
عنوان ژورنال: Lab Animal
سال: 2020
ISSN: 0093-7355,1548-4475
DOI: 10.1038/s41684-020-0510-8